shy—Drager综合征,是一种以直立性低血压为主并伴多系统受累的少见疾病。1925年Brudbury等首次报告2例。1960年shy—Drager经病理检查证实有原发性神经系统变性,因而命名为shy—Drager综合征。1969年chokroverty等称其为原发性直立性低血压。文献中尚有原发性神经源性直立性低血压和多系统萎缩症等名称。一、病因病理:shy—Drager综合征是一种原发于中枢神经系统的变性疾病。本病可导致中枢和周围植物神经功能失调。病理 shy-Drager syndrome, is a rare disease characterized by orthostatic hypotension and multiple system involvement. Brudbury et al. First reported two cases in 1925. 1960 shy-Drager confirmed by the pathological examination of primary neurological degeneration, which named shy-Drager syndrome. Chokroverty et al. In 1969 referred to it as primary orthostatic hypotension. In the literature there are primary neurogenic orthostatic hypotension and multiple system atrophy and other names. First, the etiology and pathology: shy-Drager syndrome is a degenerative disease originating in the central nervous system. The disease can cause central and peripheral autonomic dysfunction. pathology