论文部分内容阅读
含胆红素30.12%的粗品经二甲基亚矾(DMSO)溶解后,用超临界CO_2萃取除去溶剂,重结晶可获得胆红素含量大于90%的精品.本方法也适宜于其它热敏性、氧化性的生物药物的分离、提纯.
30.12% of the crude product containing bilirubin is dissolved in dimethyl sulfoxide (DMSO), and the solvent is removed by supercritical CO 2 extraction to obtain a refined product with a bilirubin content greater than 90% through recrystallization.The method is also suitable for other thermosensitive, Oxidation of biological drugs separation and purification.