N~1-乙酰氨苯磺胺(N~1-Acetylsulfanilamide),簡称磺胺乙酰。它的鈉鹽水溶液,其pH值比較接近中性,故广泛地应用于眼科治疗上。磺胺乙酰一般的制法是从磺胺开始,先用冰醋酸,后用醋酐廻流加热,生成N~1,N~4-双乙酰磺胺,再經低温水解而得磺胺乙酰。N~1,N~4-双乙酰磺胺也可以利用磺胺噻唑的副产品 N~4-磺胺乙酰用醋酐乙酰化而得。採取上述 N ~ 1-Acetaminosulfanilamide (N ~ 1-Acetylsulfanilamide), referred to as sulfa acetyl. Its sodium salt solution, the pH value is relatively neutral, it is widely used in ophthalmic treatment. Sulfa acetyl general method is from the sulfonamide, first with glacial acetic acid, followed by acetic anhydride 迴 stream heating to generate N ~ 1, N ~ 4-diacetyl sulfonamide, and then hydrolyzed to give sulfonamide. N ~ 1, N ~ 4-diacetylsulfanilamide can also be used sulfathiazole by-product N ~ 4-sulfanilic acetyl acetoxylation derived. Take the above