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目的探讨阿奇霉素序贯疗法治疗小儿支原体肺炎的临床疗效。方法选取巴中市巴州区第二人民医院2010年2月—2015年12月收治的支原体肺炎患儿110例,根据治疗方法不同将患儿分为观察组56例和对照组54例。观察组患儿予以阿奇霉素序贯疗法,对照组予以阿奇霉素静脉注射疗法,均连续治疗2~3周。比较两组患儿临床疗效、医疗费用、静脉注射阿奇霉素时间和住院时间及不良反应发生情况。结果两组患儿临床疗效比较,差异无统计学意义(P>0.05)。观察组医疗费用低于对照组,静脉注射阿奇霉素时间、住院时间短于对照组(P<0.05)。两组患儿不良反应发生率比较,差异无统计学意义(P>0.05)。结论阿奇霉素序贯疗法与静脉注射疗法治疗小儿支原体肺炎的临床疗效相当,但阿奇霉素序贯疗法治疗时间短、医药费用低,且安全性好。
Objective To investigate the clinical efficacy of sequential treatment of azithromycin in children with mycoplasma pneumonia. Methods A total of 110 children with mycoplasma pneumonia admitted from February 2010 to December 2015 in Second People’s Hospital of Bazhou District of Bazhong City were divided into observation group (56 cases) and control group (54 cases) according to different treatment methods. The observation group was given azithromycin sequential therapy, while the control group was treated with azithromycin intravenously for 2 to 3 weeks. The clinical efficacy, medical expenses, intravenous azithromycin time, hospital stay and adverse reactions were compared between the two groups. Results There was no significant difference in clinical curative effect between the two groups (P> 0.05). The cost of medical treatment in observation group was lower than that in control group. The time of intravenous injection of azithromycin and hospital stay were shorter than those of control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Sequential azithromycin and intravenous injection therapy for the treatment of children with mycoplasma pneumonia clinical efficacy, but the sequential treatment of azithromycin short treatment time, low medical costs, and good safety.