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目的探讨老年患者单纯收缩期高血压(EISH)治疗的效果。方法EISH患者50例,根据治疗前后自身对照方法,选用非洛地平缓释片和氢氯噻嗪,进行选择性联合用药,实行个体化治疗。结果治疗前后收缩压分别为(168·2±11·8)mm Hg、(123·0±11·4)mm Hg,差异有统计学意义。治疗后除血钾降低外,肾功能血脂血糖无明显变化。结论二氢吡啶类钙拮抗剂和小剂量利尿剂降压,不良反应少,降压效果好,是治疗EISH的首选。
Objective To investigate the effect of treatment of isolated systolic hypertension (EISH) in elderly patients. Methods EISH patients 50 cases, according to their own control method before and after treatment, the choice of felodipine sustained release tablets and hydrochlorothiazide, selective combination therapy, the implementation of individualized treatment. Results Before and after treatment systolic blood pressure were (168 · 2 ± 11 · 8) mm Hg and (123 · 0 ± 11 · 4) mm Hg, respectively, with significant difference. After treatment, except potassium decreased, there was no significant change in blood glucose and blood glucose in renal function. Conclusion Dihydropyridine calcium antagonist and low-dose diuretic antihypertensive, adverse reactions, antihypertensive effect, is the treatment of choice for EISH.