论文部分内容阅读
为了解慢性肝病患者机体细胞免疫功能状态,本文采用碱性磷酸酶抗碱性磷酸酶桥联酶标染色法分别检测了60例不同慢性肝病患者外周血淋巴细胞TfR及IL-2R的表达状况。结果显示,外周血淋巴细胞TfR及IL-2R表达阳性率分别是4.7±1.2%、5±1.4%(CH),8.1±1.6%、5.3+1.2%(Cir),8.1±2.3%、6.2±2%(HCC),明显低于正常对照组34±9%、36±11%(P<0.05)。本文结果提示,慢性病毒性肝炎、肝炎后肝硬化及肝癌患者细胞免疫功能低下,这可能是病毒难以清除的原因之一。
In order to understand the status of cellular immune function in patients with chronic liver disease, the expression of TfR and IL-2R in peripheral blood lymphocytes from 60 patients with chronic liver disease was detected by alkaline phosphatase-resistant alkaline phosphatase-linked enzyme-linked stain. The results showed that the positive rates of TfR and IL-2R in peripheral blood lymphocytes were 4.7 ± 1.2%, 5 ± 1.4% (CH), 8.1 ± 1.6%, 5.3 + 1.2 % (Cir), 8.1 ± 2.3% and 6.2 ± 2% (HCC), which were significantly lower than those in the control group (34 ± 9%, 36 ± 11%, P <0.05). Our results suggest that chronic viral hepatitis, posthepatitis cirrhosis and hepatocellular carcinoma in patients with cellular immune dysfunction, which may be difficult to clear the virus one of the reasons.