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目的:观察白及止血抗痨散联合西药抗结核治疗浸润型肺结核的临床疗效。方法:采用随机双盲法将符合纳入标准的70例浸润型肺结核患者分为2组各35例,对照组采取抗结核西药治疗,观察组在对照组治疗方案的基础上行白及止血抗痨散治疗,比较2组临床疗效、痰菌阴转率、不良反应及治疗前后中医症状积分。结果:观察组治疗总有效率、痰菌阴转率分别为97.1%、77.1%,高于对照组80.0%、51.4%,差异均有统计学意义(P<0.05);2组不良反应发生率比较,差异无统计学意义(P>0.05)。观察组治疗6月咳嗽、胸闷及咯血评分均低于对照组,差异均有统计学意义(P<0.05)。结论:白及止血抗痨散联合抗结核西药治疗浸润型肺结核疗效明确,痰菌阴转率较高,不良反应少。
Objective: To observe the clinical efficacy of Baihezhixue Kangxue San combined with western medicine in treating tuberculosis of infiltrative type. Methods: A total of 70 patients with infiltrative pulmonary tuberculosis that met the inclusion criteria were divided into two groups of 35 patients by randomized double-blind method. The control group was treated with anti-tuberculosis western medicine. The observation group was treated with anti-tuberculosis and anti-tuberculosis drugs on the basis of the control group. The clinical efficacy, sputum negative conversion rate, adverse reactions and TCM symptom scores before and after treatment were compared between the two groups. Results: The total effective rate of the observation group was 97.1%, sputum negative conversion rate was 77.1%, higher than the control group 80.0%, 51.4%, the difference was statistically significant (P <0.05); two groups adverse reaction rate The difference was not statistically significant (P> 0.05). The cough, chest tightness and hemoptysis scores in the observation group were lower than those in the control group in June, with statistical significance (P <0.05). Conclusion: Baihejiedujiexuejie combined with anti-tuberculosis western medicine treatment of infiltrative pulmonary tuberculosis clear effect, sputum negative conversion rate is higher, less adverse reactions.