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目的:观察有氧运动联合加减苍附导痰汤对痰湿型多囊卵巢综合征伴胰岛素抵抗(PCOS-IR)的改善作用。方法:选取60例痰湿型PCOS-IR为研究对象,采用随机数字表法分为对照组和实验组各30例。对照组给予加减苍附导痰汤治疗,实验组在对照组用药基础上配合有氧运动治疗。2组均治疗3月。观察2组临床疗效,治疗前后中医证候积分、多毛和痤疮评分,以及体重指数(BMI)的变化。结果:治疗前,2组各项中医证候积分及总积分比较,差异均无统计学意义(P>0.05)。治疗后,实验组月经量和对照组月经周期、月经量积分虽较治疗前均有下降趋势,但差异均无统计学意义(P>0.05),其余各项证候积分及总积分均较治疗前降低(P<0.05);除实验组月经周期积分低于对照组外(P<0.05),其余各项证候积分及总积分与对照组比较,差异均无统计学意义(P>0.05)。治疗前,2组多毛、痤疮评分及BMI比较,差异均无统计学意义(P>0.05)。治疗后,2组多毛、痤疮评分均未改善(P>0.05),BMI均较治疗前降低(P<0.05);实验组的BMI低于对照组(P<0.05)。结论:有氧运动联合加减苍附导痰汤能改善痰湿型PCOS-IR患者的中医证候,是一种预防和治疗PCOS-IR患者代谢紊乱的有效方案。
Objective: To observe the effect of aerobic exercise combined with Canshuantanshutang on the improvement of phlegm-damp polycystic ovary syndrome with insulin resistance (PCOS-IR). Methods: Sixty cases of phlegm - damp type PCOS - IR were selected as the research object and divided into control group and experimental group by random number table. The control group was treated with addition and subtraction Cang Guotan sputum treatment group in the control group on the basis of medication with aerobic exercise therapy. 2 groups were treated for 3 months. The clinical curative effect, TCM syndrome score before and after treatment, hirsutism and acne score, and body mass index (BMI) were observed. Results: Before treatment, there was no significant difference in TCM syndrome scores and total scores between the two groups (P> 0.05). After treatment, the menstrual flow in the experimental group and the menstrual cycle and menstrual cycle in the control group showed a downward trend compared with that before treatment, but the difference was not statistically significant (P> 0.05), and the remaining syndromes and total points (P <0.05). The scores of other syndromes and total points in the experimental group were lower than those in the control group (P <0.05), but there was no significant difference between the other syndromes and the control group (P> 0.05) . Before treatment, there were no significant differences in hairiness, acne score and BMI between the two groups (P> 0.05). After treatment, the hairiness and acne scores were not improved in both groups (P> 0.05). The BMI was lower than that before treatment (P <0.05). The BMI in the experimental group was lower than that in the control group (P <0.05). Conclusion: Aerobic exercise combined with Cang Cailin with Phlegm-Stomach Decoction can improve TCM syndromes of phlegm-damp PCOS-IR patients. It is an effective way to prevent and treat metabolic disorders in PCOS-IR patients.