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目的 探讨血清心肌肌钙蛋白 (c Tn )评估创伤性窒息对心肌损害的临床价值。方法 采用 EL ISA法对 31例创伤性窒息患儿和 2 3例正常儿童进行 c Tn 检测 ,同时检测肌酸磷酸激酶同工酶 (CK- MB)。结果 创伤性窒息组急性期血清c Tn 、CK- MB水平明显高于对照组 (P<0 .0 1) ,且与窒息程度有关 ,c Tn 诊断创伤性窒息心肌损伤的特异性优于 CK- MB。结论 血清 c Tn 和 CK- MB的测定有助于早期预测心肌细胞损害 ,c Tn 优于 CK- MB。
Objective To investigate the clinical value of serum cardiac troponin (cTn) in evaluating traumatic asphyxia on myocardial damage. Methods Thirty-one children with traumatic asphyxia and 23 normal children were tested for cTn by ELISA method and creatine phosphokinase isoenzyme (CK-MB). Results The levels of cTn and CK-MB in acute traumatic asphyxia group were significantly higher than those in control group (P <0.01), and were related to the degree of asphyxia. The specificity of CTn in the diagnosis of traumatic asphyxia myocardial injury was better than CK- MB. Conclusion The determination of serum cTn and CK-MB can be used to predict myocardial damage in the early stage, and cTn is superior to CK-MB.