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目的研究尿激酶冲击溶栓治疗急性脑梗塞的疗效。方法用尿激酶冲击溶栓治疗３０例急性脑梗塞与常规用维脑路通治疗３２例急性脑梗塞进行比较，两组间年龄、性别及治疗前神经功能缺损程度无明显差异（Ｐ＞０．０５）。结果尿激酶组神经功能恢复明显优于对照组（Ｐ＜０．０１），尿激酶可明显降低血浆纤维蛋白原水平，在治疗过程中无明显不良反应，治疗后总有效率尿激酶组为８６．７％，对照组４６．９％，差异显著（Ｐ＜０．０１）。结论对于发病在１２ｈ内急性脑梗塞应尽快进行溶栓治疗，以期改善脑梗塞的预后。
Objective To study the curative effect of thrombolytic therapy of urokinase on acute cerebral infarction. Methods Thirty patients with acute cerebral infarction treated with thrombolytic therapy of urokinase and 32 patients with conventional cerebral infarction treated with venom were compared. There was no significant difference in age, sex and preoperative neurological deficit between the two groups (P> 0.05). 05). Results The recovery of neurological function of urokinase group was significantly better than that of the control group (P <0.01). Urokinase could significantly reduce the level of plasma fibrinogen without obvious adverse reactions in the course of treatment. After treatment, the total effective urokinase group was 86 .7% in control group and 46.9% in control group, with significant difference (P <0.01). Conclusion For acute cerebral infarction within 12h, thrombolytic therapy should be carried out as soon as possible so as to improve the prognosis of cerebral infarction.