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以聚乙烯醇(PVA)、聚氧乙烯(PEO)和3-氯-2-羟丙基三甲基氯化铵壳聚糖(HACC)为原料通过辐射交联法制备出一种新型壳聚糖水凝胶敷料(HACC/PVA/PEO),探讨了不同辐照剂量以及物料比对其性能的影响,并用红外和扫描电镜进行了结构表征.结果表明,当辐照强度为40kGy,壳聚糖季铵盐(HACC)与聚乙烯醇(PVA)/聚氧化乙烯(PEO)共混物料比为1∶1(质量比)时,水凝胶的抗张强度达3.2 MPa,且具备理想的溶胀性能以及水蒸发率,对大肠杆菌和金黄色葡萄球菌均有一定的抑制作用.
A new type of shell poly (vinyl alcohol) (PVA), polyethylene oxide (PEO) and 3-chloro-2-hydroxypropyl trimethyl ammonium chloride chitosan (HACC) (HACC / PVA / PEO), the effects of different irradiation dose and material ratio on the properties of HACC / PVA hydrogel dressing were investigated, and their structures were characterized by IR and scanning electron microscopy.The results showed that when the irradiation intensity was 40kGy, When the ratio of HACC to PVA / PEO is 1: 1 (mass ratio), the hydrogel has a tensile strength of 3.2 MPa and ideal swelling Performance and water evaporation rate, have a certain inhibition of E. coli and Staphylococcus aureus.