在克山病病因及发病机制研究中,有证据表明克山病是一种生物地球化学性疾病,属于缺血缺氧性心肌坏死性疾病。已知亚硝酸盐中毒可引起动物缺氧性心肌坏死,病理形态学上与克山病的心肌坏死类似。 实验研究还证明克山病病区粮食中存在着致病因素,且与亚硝酸盐之间有着特殊的 Keshan disease etiology and pathogenesis in the study, there is evidence that Keshan disease is a biogeochemical disease, is hypoxic ischemic myocardial necrosis disease. Nitrite poisoning is known to cause hypoxic myocardial necrosis in animals and is similar in pathological morphology to myocardial necrosis of Keshan disease. Experimental studies have also proved that there are pathogenic factors in food of Keshan disease, and there is a special