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业已证明,大剂量(300~1500mg/d)阿斯匹林(Aspirin)能显著降低短暂性脑缺血发作(TIA),小剂量Aspirin正逐渐应用于临床。本文旨在通过应用不同剂量(50~500mg/d)Aspirin治疗急性缺血性脑血管病(AICVD),探寻其微小有效剂量。材料与方法一、对象。AICVD病人30例,男22例,女8例,年龄64.27岁(42~85岁)。按随机化原则分三组,每组10例,抽血前一月均未服用过影响血小板功能及前列腺素(PGS)代谢的药物。二、材料与方法。 (一) 药品:Aspirin,50mg/片,湖北医学院
Aspirin has been shown to significantly reduce transient ischemic attacks (TIA) at high doses (300-1500 mg / d), and small doses of Aspirin are increasingly being used clinically. The purpose of this article is to explore the effective dose of Aspirin in patients with acute ischemic cerebrovascular disease (AICVD) by applying different doses (50 ~ 500mg / d) of Aspirin. Materials and methods First, the object. AICVD patients in 30 cases, 22 males and 8 females, aged 64.27 years (42 to 85 years old). Randomized according to the principle of three groups, 10 cases in each group, a month before the blood had taken affect platelet function and prostaglandin (PGS) metabolism of drugs. Second, materials and methods. (A) drugs: Aspirin, 50mg / tablet, Hubei Medical College