胚泡的成功种植、妊娠的维持和分娩的发动被视为依赖于对一组外来抗原炎性反应的适时调节过程。Cachectin-肿瘤坏死因子α(tumor necro-sis factor α;TNF-α)是一种作为局部炎性介质并参与组织再造的细胞激活素(Cytokine)。蜕膜产生的局部 TNF-α或许是子宫炎性反应和生殖成功的调节中心。为明确人类蜕膜在对细菌脂多糖(LPS)反应中是否产生 TNF-α,选择9例无妊娠并发症、择期再次剖宫产前未发动分娩的足月孕妇,于剖宫产时避免胎盘接触皮肤及其它潜在内毒素源,于胎盘娩出后立即以无菌钳剥取附贴于绒 The successful implantation of blastocysts, the maintenance of pregnancy, and the initiation of childbirth are considered to depend on the timely regulation of the inflammatory response to a panel of foreign antigens. Cachectin-tumor necrosis factor-α (TNF-α) is a cytokine that is involved in tissue remodeling as a local inflammatory mediator. Local TNF-α produced by decidua may be the center of regulation of uterine inflammatory response and reproductive success. In order to clarify whether human decidua produces TNF-α in response to bacterial lipopolysaccharide (LPS), nine full-term pregnant women with no complications of pregnancy and elective cesarean section before elective delivery were also selected to avoid placenta during cesarean section Contact with skin and other potential source of endotoxin, immediately after delivery of the placenta with sterile forceps attached to the velvet