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目的探讨TRUST和TPPA联合检测对梅毒的监控和诊治价值,为临床诊治梅毒提供实验依据。方法采用TRUST法和TPPA法测定2 083例血清标本(其中910例梅毒患者血清)。结果对910例梅毒患者血清检测,TRUST法检出773例阳性,敏感性为84.9%,特异性为96.1%。TPPA法检出899例阳性,敏感性为98.7%,差异有统计学意义(P<0.05);TPPA法具有很高的特异性和灵敏度。结论 TRUST和TPPA联合检测为临床诊治梅毒提供更有价值的实验依据,更有利于梅毒的监控和诊治。
Objective To investigate the value of TRUST and TPPA in the surveillance, diagnosis and treatment of syphilis and provide experimental evidence for clinical diagnosis and treatment of syphilis. Methods The serum samples of 2 083 cases (including 910 cases of syphilis serum) were detected by TRUST method and TPPA method. Results Serum samples from 910 patients with syphilis were detected by TRUST, 773 were positive with TRUST, with a sensitivity of 84.9% and a specificity of 96.1%. There were 899 positive cases detected by TPPA, the sensitivity was 98.7%, the difference was statistically significant (P <0.05). The TPPA method had high specificity and sensitivity. Conclusion Combined detection of TRUST and TPPA provides more valuable experimental evidences for clinical diagnosis and treatment of syphilis, and is more conducive to the monitoring and diagnosis of syphilis.