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制备动物模型是研究休克机制和评价药物疗效的常用方法。研究人员大多根据各类休克的发病原因、机制及临床表现特征来复制病理模型。本文对休克的分类和特点,不同休克动物模型的建立及休克动物模型在药物研究中的应用作一综述。
Animal models are commonly used to study the mechanism of shock and evaluate the efficacy of the drug. Researchers are mostly based on the pathogenesis of various types of shock, mechanisms and clinical features to reproduce the pathological features. This article reviews the classification and characteristics of shock, the establishment of different animal models of shock and the application of animal models of shock in the study of drugs.