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目的分析湖北省艾滋病病毒(HIV)感染者/艾滋病(AIDS)病人(HIV感染者/AIDS病人)的死亡情况。方法从艾滋病综合防治管理系统下载湖北省病例报告历史卡片,选择录入日期在2004-2013年且现住址为湖北省的死亡病例进行分析。结果 2004-2013年,报告现住址为湖北省的HIV感染者/AIDS病人死亡2 592例,男女比例为1.93∶1,平均年龄(44.4±13.9)岁,感染途径主要为异性传播,占53.67%。其中68.75%(1 782/2 592)在确认1年内死亡。死亡前进行了CD4~+T淋巴细胞检测占55.36%(1 435/2 592),死亡前进行过高效抗反转录病毒治疗(HAART)占19.52%(506/2 592),平均服药时间为1.63年,平均生存时间2.41年。CD4~+T淋巴细胞水平在50个/μl、50~200个/μl、200~350个/μl和350个/μl各组间生存时间差异有统计学意义(P<0.05)。因AIDS、非AIDS其他疾病、吸毒过量、其他原因而死亡分别占48.4%、21.9%、1.0%、5.1%,还有23.6%的死亡原因不详。结论 2004-2013年湖北省HIV感染者/AIDS病人死亡病例逐年增加。AIDS相关疾病是导致HIV感染者/AIDS病人死亡的主要原因。需要早期发现病例,早期诊断和早期治疗,提高死亡原因的报告质量。
Objective To analyze the death of HIV / AIDS patients (HIV infected persons / AIDS patients) in Hubei Province. Methods Hubei Provincial Case History Card was downloaded from the integrated HIV / AIDS prevention and control system and the death cases in Hubei Province from 2004 to 2013 were selected. Results Between 2004 and 2013, 2 592 HIV / AIDS patients in Hubei province reported a death rate of 1.93:1, with an average age of (44.4 ± 13.9) years. The main route of infection was heterosexual transmission, accounting for 53.67% . Of these, 68.75% (1 782/2 592) died within 1 year of confirmation. The percentage of CD4 ~ + T lymphocytes detected before death was 55.36% (1 435/2 592), 19.52% (506/2 592) of patients were treated with highly effective antiretroviral therapy before death (506/2 592), and the average medication time was 1.63 years, the average survival time of 2.41 years. The survival time of CD4 ~ + T lymphocytes in 50 / μl, 50 ~ 200 / μl, 200 ~ 350 / μl and 350 / μl groups was significantly different (P <0.05). The causes of death due to AIDS, non-AIDS other diseases, excessive drug consumption and other causes accounted for 48.4%, 21.9%, 1.0%, 5.1% and 23.6% respectively. Conclusion The deaths of HIV / AIDS patients in Hubei Province from 2004 to 2013 have been increasing year by year. AIDS-related diseases are the leading cause of death in people living with HIV / AIDS. Need early detection of cases, early diagnosis and early treatment, improve the quality of the report of the cause of death.