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目的:探讨莫西沙星治疗老年下呼吸道感染的疗效及安全性。方法:60例老年下呼吸道细菌感染患者,随机分为实验组(30例)和对照组(30例)。实验组给予盐酸莫西沙星氯化钠注射液250mL,1次/d,静脉滴注;对照组给予盐酸左氧氟沙星氯化钠注射液100mL,2次/d,静脉滴注;疗程均为7～14d。结果:实验组总有效率93.33%,对照组总有效率66.67%,2组比较差异有统计学意义(P<0.05)。实验组的不良反应发生率为10.0%,对照组的不良反应发生率为13.33%,2组比较差异无统计学意义(P>0.05)。结论:莫西沙星治疗老年下呼吸道感染安全、有效。
Objective: To investigate the efficacy and safety of moxifloxacin in the treatment of lower respiratory tract infection in the elderly. Methods: Sixty elderly patients with lower respiratory tract bacterial infection were randomly divided into experimental group (30 cases) and control group (30 cases). The experimental group was given moxifloxacin hydrochloride sodium chloride injection 250mL, 1 / d, intravenous infusion; the control group was given levofloxacin hydrochloride sodium chloride injection 100mL, 2 times / d, intravenous infusion; treatment were 7 ~ 14d . Results: The total effective rate was 93.33% in the experimental group and 66.67% in the control group. The difference between the two groups was statistically significant (P <0.05). The incidence of adverse reactions in the experimental group was 10.0%, while that in the control group was 13.33%. There was no significant difference between the two groups (P> 0.05). Conclusion: Moxifloxacin is safe and effective in treating elderly lower respiratory tract infection.