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目的:探讨多巴酚丁胺联合酚妥拉明治疗慢性肺源性心脏病急性发作期的疗效及临床分析。方法:2010年9月至2011年9月期间,我院诊治的60例慢性肺源性心脏病急性发作期患者,随机将其分为对照组(常规治疗)和观察组(对照组基础上,给予多巴酚丁胺联合酚妥拉明治疗),对两组临床疗效、心电图改善情况,以及肺功能指标,进行观察和比较。结果:与对照组相比,观察组总有效率、FVC,FEV1和FEV1/FVC等肺功能指标均显著升高,肺型P波和肢导QRS低电压例数明显减少,P<0.05。结论:对于慢性肺源性心脏病急性发作期患者,多巴酚丁胺联合酚妥拉明治疗的疗效显著,明显改善患者的肺功能,值得临床推广。
Objective: To investigate the efficacy and clinical analysis of dobutamine combined with phentolamine in the treatment of acute episode of chronic cor pulmonale. Methods: From September 2010 to September 2011, 60 patients with acute exacerbation of chronic cor pulmonale treated in our hospital were randomly divided into control group (routine treatment) and observation group (on the basis of control group, Given dobutamine combined with phentolamine treatment), the two groups of clinical efficacy, ECG improvement, and lung function indicators were observed and compared. Results: Compared with the control group, the total effective rate, the pulmonary function indexes such as FVC, FEV1 and FEV1 / FVC in the observation group were significantly increased, and the P wave and pulmonary QRS low voltage cases in the observation group were significantly decreased (P <0.05). Conclusion: The efficacy of dobutamine combined with phentolamine in patients with acute episodes of chronic cor pulmonale is significant, and the lung function of patients with pulmonary edema is significantly improved, which is worthy of clinical promotion.