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目的 :探讨江苏男男性行为人群人类免疫缺陷病毒(HIV)感染的潜伏期及其影响因素。方法:采用双向性队列研究,选择江苏省南京和镇江两市有明确HIV感染时间、经男男性接触途径感染艾滋病(AIDS)的病例,应用Kaplan-Meier乘积极限法计算潜伏期,用COX回归模型探讨AIDS发病的影响因素。结果:本次调查观察到男男性行为人群HIV感染者的平均潜伏期为(46.129±2.795)个月,95%可信区间为40.651~51.606个月,多因素COX回归分析显示,基线CD4、半年CD4值较高是延迟进入AIDS发病期的保护因素。结论:江苏省男男性行为人群潜伏期短于国内外既往文献报道经其他途径传播的AIDS潜伏期,建议在有条件的情况下对男男性行为人群提供相应的卫生服务,通过早期治疗,延长其生存时间,提高生存质量。
Objective: To investigate the incubation period and its influencing factors of human immunodeficiency virus (HIV) infection among men who have sex with men in Jiangsu Province. Methods: A two-way cohort study was conducted to select the cases of HIV infection in MSM in Nanjing and Zhenjiang in Jiangsu Province. The latent period was calculated by the Kaplan-Meier product limit method and the COX regression model was used Influencing factors of AIDS. Results: The average latency of HIV-infected men who had MSM was (46.129 ± 2.795) months and the 95% confidence interval was 40.651 to 51.606 months. Multivariate COX regression analysis showed that baseline CD4, A higher value is a protective factor that delays the onset of AIDS. Conclusion: The incubation period of MSM population in Jiangsu province is shorter than that of other AIDS-infected individuals in previous literature both at home and abroad. It is suggested to provide corresponding health services to MSM population under the condition that there is a condition, and to prolong its survival time through early treatment , Improve the quality of life.