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为了研究精浆内细胞因子对男性生育能力的影响，通过对男性不育患者和正常生育男性精浆内细胞因子含量的测定（ Ｅ Ｌ Ｉ Ｓ Ａ） ，发现少精和无精不育患者伴有生殖系特异感染（ 支原体、衣原体、淋球菌） 时细胞因子（ Ｉ Ｌ１ ， Ｔ Ｎ Ｆα， Ｉ Ｌ６） 的水平明显高于无生殖系特异感染的不育患者和正常男性，差异有极显著性（ Ｐ＜ ０ ．００１） ，显示在炎症特别是性传播疾病时所产生的细胞因子与男性不育有密切相关性，说明精浆内明显表达不同的细胞因子可能参与影响精子功能，是导致男性不育的原因之一。
In order to study the effects of cytokines in seminal plasma on fertility in men, we measured the levels of cytokines in male infertility and normal seminal plasma (ELISAs) and found that patients with oligospermia and azoospermia The levels of cytokines (I L1, T N Fα, I L6) were significantly higher in patients with genital specific infection (Mycoplasma, Chlamydia, Neisseria gonorrhoeae) than in infertile patients without genital infection and normal males , The difference was significant (P <0.001), showing that the cytokines produced in the inflammation, especially sexually transmitted diseases and male infertility are closely related, indicating that significant expression of different seminal plasma cytokines may be involved in the impact Sperm function is one of the causes of male infertility.