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目的探讨阿奇霉素治疗小儿肺炎的临床疗效。方法选取2005—2013年和顺县中医院收治的小儿肺炎患儿298例,随机分为观察组与对照组,各149例。观察组患者予以阿奇霉素治疗,对照组患者予以红霉素治疗。观察两组患者临床疗效、临床症状体征消失时间、平均住院时间及不良反应发生情况。结果观察组患儿总有效率高于对照组,差异有统计意义(P<0.01);观察组患儿喘鸣消失时间、咳嗽消失时间、退热时间、住院时间短于对照组,治疗10d胸片吸收率高于对照组,差异均有统计学意义(P<0.01);观察组患儿不良反应发生率低于对照组(P<0.01)。结论阿奇霉素治疗小儿肺炎的临床疗效显著,能改善患儿临床症状,缩短住院时间,且不良反应小。
Objective To investigate the clinical efficacy of azithromycin in treating children with pneumonia. Methods 298 cases of pediatric pneumonia admitted from 2005 to 2013 in Heshun Hospital of Traditional Chinese Medicine were randomly divided into observation group and control group with 149 cases each. Patients in the observation group were treated with azithromycin and patients in the control group were treated with erythromycin. Clinical efficacy, clinical symptoms and signs of disappearance of time, average length of stay and adverse reactions were observed. Results The total effective rate of the observation group was higher than that of the control group (P <0.01). The disappearance of wheezing, disappearance of cough, the time of fever relief and hospital stay in the observation group were shorter than those in the control group, (P <0.01). The incidence of adverse reactions in the observation group was lower than that in the control group (P <0.01). Conclusion The clinical efficacy of azithromycin in treating pediatric pneumonia is significant, which can improve the clinical symptoms, shorten the length of stay in hospital and reduce the adverse reactions.