目的　探讨危重病患者血糖、血胰岛素及胰岛素抵抗与病情程度的相关性。方法　观察 30例危重病患者急性期与稳定期空腹血糖、血胰岛素及胰岛素敏感指数 ,并进行比较。结果　危重病患者稳定期较急性期血糖及血胰岛素水平降低 ,胰岛素敏感指数升高 ,差异有显著性。结论　危重病患者存在高血糖及胰岛素抵抗 ,且与病情严重程度有关 Objective To investigate the correlation between blood glucose, blood insulin and insulin resistance and severity of illness in critically ill patients. Methods The fasting blood glucose, blood insulin and insulin sensitivity index in 30 critically ill patients were observed and compared. Results Compared with the acute stage, the patients with critical illness had lower blood glucose and blood insulin levels and a higher insulin sensitivity index, the difference was significant. Conclusions The critically ill patients have hyperglycemia and insulin resistance, and are related to the severity of the disease