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目的 评价拉米夫定治疗慢性乙型肝炎生存质量的改善状况。方法 分别于拉米夫定治疗前、治疗半年、1年采用SF 3 6量表测定 2 44例病人的生存质量评分。结果 与治疗前相比 ,拉米夫定治疗半年及 1年后在躯体角色RP( 9.6)、社会功能SF( 8.2 )、情绪角色RE( 11.8)和活力VT( 6.2 ) 4个领域得分有显著提高 (P <0 .0 5 ) ,主要集中在心理状态评分MCS( 3 .6)。结论 拉米夫定治疗慢性乙型肝炎病人能有效改善病人生存质量。
Objective To evaluate the improvement of quality of life in patients with chronic hepatitis B treated with lamivudine. Methods Before and after lamivudine treatment, six months and one year of SF 3 6 were used to measure the quality of life of 444 patients. Results Compared with those before treatment, lamivudine had significant scores in the four fields of body function RP (9.6), social function SF (8.2), emotional role RE (11.8) and activity VT (6.2) (P <0.05), mainly in the mental state score MCS (3.6). Conclusion lamivudine treatment of chronic hepatitis B patients can effectively improve the quality of life of patients.