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机体在衰老过程中,出现各种功能衰退和生理紊乱现象,学习记忆伴随机体老化,也出现了明显的减退,严重者还可发展为痴呆,影响了老年人的生活质量。祖国医学认为“肾虚、血瘀、痰阻”是主要原因。临床应用补肾活血化痰法治疗老年痴呆取得了良好效果。实验研究从补肾、补肾活血或化痰入手较多,而将补肾、化痰、活血三者结合,观察其对衰老动物学习记忆能力的影响尚未见报道。本实验应用自然衰老和D-半乳糖(D-gal)衰老模型动物,观察补肾化痰活血方对衰老动物学习记忆能力减退的改善作用,验证了本方的疗效,为临床用药原则提供了实验室依据。
During the aging process, the body experiences various functional declines and physiological disorders. Learning and memory are accompanied by aging of the body, and there are also obvious declines. Severe persons may develop dementia and affect the quality of life of the elderly. The motherland medicine believes that “kidney deficiency, blood stasis, and obstruction” are the main reasons. Clinical application of Bushen Huoxue Huayu therapy for senile dementia has achieved good results. The experimental study started from kidney-busting, kidney-invigorating, blood-activating, or phlegm-removal. However, the combination of kidney-invigorating, phlegm-removing, and blood-activating was observed, and it has not been reported that the effect on the learning and memory ability of aging animals has been reported. In this experiment, natural aging and D-galactose (D-gal) aging model animals were used to observe the effect of Bushen Huayu Huoxue Fang on improving the learning and memory abilities of aging animals. The efficacy of this prescription was verified, and an experiment was provided for the principle of clinical medication. Room basis.