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目的探讨二氯化锶联合唑来膦酸在多发性骨转移癌治疗中的临床效果。方法选取2014年8月至2015年8月我院收治的多发性骨转移癌患者86例作为研究对象,按照随机平均原则将其分为对照组(n=43)和观察组(n=43),其中对照组采用放射性核素二氯化锶治疗,观察组采用二氯化锶联合唑来膦酸给予治疗,对两组患者骨痛缓解和生活质量进行观察和比较。结果治疗后,观察组患者的骨痛缓解总有效率为81.4%,生活质量总改善率为88.37%,均明显优于对照组(P<0.05),差异有统计学意义。结论二氯化锶联合唑来膦酸治疗多发性骨转移癌的临床效果良好,患者的骨转移减少,骨痛得到缓解,同时生活质量得到明显改善,在临床治疗中值得进一步借鉴。
Objective To investigate the clinical effect of strontium dichloride combined with zoledronic acid in the treatment of multiple bone metastases. Methods Eighty-six patients with multiple bone metastases who were treated in our hospital from August 2014 to August 2015 were selected as the research object and divided into control group (n = 43) and observation group (n = 43) according to the randomized average principle , In which the control group was treated with strontium chloride, and the observation group was treated with strontium chloride combined with zoledronic acid. The relief of pain and the quality of life were observed and compared between the two groups. Results After treatment, the total effective rate of bone pain relief in the observation group was 81.4%, and the total quality of life improvement rate was 88.37%, which were significantly better than the control group (P <0.05). The difference was statistically significant. Conclusion Strontium chloride combined with zoledronic acid is effective in the treatment of multiple bone metastases. The bone metastases of patients with bone metastases are reduced, bone pain is relieved, and the quality of life is significantly improved. Therefore, it is worth further reference in clinical treatment.