论文部分内容阅读
目的:探讨液基细胞学在宫颈病变机会性筛查中的诊断价值。方法:回顾分析2011年1—12月份宫颈病变妇女接受TCT检查、阴道镜下宫颈活检342例临床资料,分析细胞学检测结果与病理学检查结果的符合率。结果:342例患者中细胞学检查结果炎症102例,ASCUS(AGUS)123例,LSIL 77例,HSIL 35例,SCC(AC)5例。组织学结果炎症222例,CINⅠ56例,CINⅡ—Ⅲ56例,SCC(AC)8例。细胞学与组织学总体符合率为77.17%。细胞学结果正常、LSIL、HSIL中与组织学符合率分别为96.08%、49.35%、80%。TCT的诊断准确性为90.87%,特异性为85.97%,阳性预测值为86.32%,阴性预测值为96.08%。结论:液基细胞学在宫颈病变机会性筛查中的具有较高的灵敏度,TCT作为宫颈病变的筛查方法与组织学活检病理学方法比较,具有较高的特异性和准确性,尤其是细胞学正常与高级别上皮内瘤变病例。阴道镜协同TCT检查可明显提高宫颈癌前病变的诊断率。
Objective: To investigate the diagnostic value of liquid-based cytology in the screening of opportunistic cervical lesions. Methods: A retrospective analysis of January 2011 women with cervical lesions from January to December 2011 TCT, colposcopic cervical biopsy 342 cases of clinical data, analysis of cytology results and pathological findings in line with the rate. Results: There were 102 inflammatory cytology findings in 123 patients, 123 ASCUS (AGUS), 77 LSIL, 35 HSIL and 5 SCC (AC). Histological findings 222 cases of inflammation, CINⅠ56 cases, CINⅡ-Ⅲ56 cases, SCC (AC) in 8 cases. The overall coincidence rate of cytology and histology was 77.17%. Cytology results were normal, LSIL, HSIL and histological coincidence rates were 96.08%, 49.35%, 80%. The diagnostic accuracy of TCT was 90.87%, the specificity was 85.97%, the positive predictive value was 86.32% and the negative predictive value was 96.08%. CONCLUSION: Liquid-based cytology has high sensitivity in opportunistic screening of cervical lesions. TCT as a screening method for cervical lesions compared with histological biopsy pathology has high specificity and accuracy, especially Cytology normal and high-grade cases of intraepithelial neoplasia. Collagen colposcopy with TCT can significantly improve the diagnostic rate of cervical precancerous lesions.