血小板内只含有少量游离的花生四烯酸(AA),而多数却连接在磷脂上,当血小板受到诱导剂刺激时,AA则从膜磷脂上释放出来。已知AA释放可能涉及到三个不同的机理。不同的诱导剂在诱导AA释放时,其途径亦可能不尽相同。本文通过测定AA环氧酶途径代谢产物—TXB_2,比较了胶原和ADP诱导AA释放的差异。 Platelets contain only a small amount of free arachidonic acid (AA), while the majority are connected to phospholipids, AA is released from membrane phospholipids when stimulated by an inducer of platelets. It is known that AA release may involve three different mechanisms. Different inducers may also have different pathways when they induce AA release. In this paper, we measured the difference between collagen and ADP-induced AA release by measuring the metabolites of TXA pathway.