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目的探讨三维适形放疗结合腔内后装放疗在宫颈癌治疗中的疗效。方法自2004年5月至2006年5月对收治的70例Ⅱ期以上宫颈癌患者采用三维适形放疗治疗,使90%等剂量曲线包绕靶区,肿瘤剂量45Gy,腔内照射5～6次,A点总剂量75～81Gy。结果 70例宫颈癌患者总有效率为97.1%。5a以上生存率27.1%(19/70),3a以上生存率77.1%(54/70),1a以上生存率100%(70/70)。结论三维适形放疗结合腔内后装放疗治疗宫颈癌可提高靶区剂量,周围器官得到有效保护,放射反应小,治疗精度高,显著提高了肿瘤局部控制率和生存率,提高患者对放疗的耐受性。
Objective To investigate the effect of three-dimensional conformal radiotherapy combined with endovascular radiotherapy in the treatment of cervical cancer. Methods From May 2004 to May 2006, 70 patients with stage Ⅱ or higher cervical cancer were treated with three-dimensional conformal radiotherapy. The 90% isodose curve was wound around the target area with a tumor dose of 45 Gy and intraluminal irradiation of 5 to 6 Times, A total dose of 75 ~ 81Gy. Results The total effective rate of 70 cases of cervical cancer was 97.1%. The survival rate was higher than 5a (27.1%, 19/70), the survival rate was above 77.1% (54/70) and the survival rate above 1a was 100% (70/70). Conclusion Three-dimensional conformal radiotherapy combined with intracavitary posterior radiation therapy for cervical cancer can increase the target dose, the surrounding organs are effectively protected, the radiation response is small, the treatment accuracy is high, the tumor local control rate and survival rate are significantly increased, and the patients’ Tolerance.