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用ＰＩＸＥ方法测定了四川省四个不同硒水平的克山病区和非克山病区的６－１１岁健康儿童红血球中铷（Ｒｂ）含量，发现克山病区儿童红血球中Ｒｂ含量高于其它三个地区。同时用辅酶Ⅱ（ＮＡＤＰＨ）偶联法测定含硒酶谷胱甘肽过氧化酶（ＧＳＨＰｘ）的活力，证明克山病区儿童确处于低硒状态。两年后，又用中子活化法测定了克山病区和补硒控制发病的老病区的大米和土壤中的Ｒｂ含量，发现克山病区的大米和土壤中Ｒｂ含量也显著高于补硒地区，说明克山病区儿童红血球中Ｒｂ含量高是由于摄入Ｒｂ水平高所致。
The Rb contents of erythrocytes from 6-11-year-old healthy children in Keshan ward and non-Keshan ward of four different selenium levels in Sichuan province were detected by PIXE method. The content of Rb in red blood cells of Keshan ward children was higher than The other three areas. Coenzyme Ⅱ (NADPH) coupling method was also used to determine the activity of selenium-containing enzyme glutathione peroxidase (GSHPx), confirming that children in Keshan disease area are indeed in a low selenium state. Two years later, the content of Rb in rice and soil of Keshan ward and the old diseased ward of selenium control was measured by neutron activation method. The content of Rb in rice and soil of Keshan ward was also significantly higher than that of complement Selenium area, indicating that high levels of Rb in children’s erythrocytes in Keshan ward is due to the high level of Rb intake.