氨基糖甙类(Aminoglucosides)抗生素系化学结构含有氨基糖分子的一类抗生素。这类抗生素品种较多,临床用途较广,目前用于临床的主要有链霉素、庆大霉素、卡那霉素(包括妥布霉素、丁胺卡那霉素等)、新霉素及巴龙霉素五类。其共同特点为:1.它们的化学结构中含有多个氨基或胍基碱性基团,是较强的有机碱,故临床多用其硫酸盐。这类药物离解度大,脂溶度小,不易被胃肠道吸收,不易透过血脑屏障,主要分布于细 Aminoglucosides Antibiotics A class of antibiotics that contain amino sugar molecules in their chemical structure. More varieties of these antibiotics, a wide range of clinical uses, currently used clinically mainly streptomycin, gentamicin, kanamycin (including tobramycin, amikacin, etc.), Neoformans Prime and paromomycin five categories. Their common characteristics are: 1. Their chemical structure contains more than one amino or guanidine basic groups, is a strong organic base, so the clinical use of its sulfate. Such drugs large degree of dissociation, fat solubility, not easily absorbed by the gastrointestinal tract, difficult to penetrate the blood-brain barrier, mainly in thin