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目的 探讨全胃切除术治疗胃底贲门癌的治疗效果。 方法 对 1990年 1月至 2 0 0 3年12月间收治的 4 80例胃底贲门癌患者的临床资料进行回顾性分析 ,其中全胃切除组 (A组 ) 2 90例 ,近侧胃大部分切除术 (B组 ) 190例。 结果 A组 1、3、5年生存率分别为 83.8%、6 0 .8%、38.3% ,B组分别为 79.2 %、4 8.3%、2 3.3% ,两组 3、5年生存率有显著性差异 (P <0 .0 5 )。A组术后并发症的发生率和病死率分别为 13.8%和 2 .4 % ,B组分别为 11.6 %和 2 .1% ,两组无统计学差异 (P >0 .0 5 )。 结论 全胃切除术治疗胃底贲门癌能提高疗效 ,不会增加术后并发症发生率和病死率 ,且能明显提高生存率。
Objective To investigate the effect of total gastrectomy in the treatment of gastric cardia cancer. Methods A retrospective analysis was performed on the clinical data of 480 gastric cardia patients admitted between January 1990 and December 2003. The total gastrectomy group (group A, 290 cases), the proximal gastric mass Partial resection (group B) 190 cases. Results The 1, 3, 5-year survival rates in group A were 83.8%, 60.8% and 38.3%, respectively, and those in group B were 79.2%, 48.3% and 23.3% Sex differences (P <0.05). The incidence of postoperative complications and mortality in group A were 13.8% and 2.4% respectively, while those in group B were 11.6% and 2.1% respectively. There was no significant difference between the two groups (P> 0.05). Conclusion Total gastrectomy in the treatment of gastric cardia cancer can improve the curative effect, will not increase the incidence of postoperative complications and mortality, and can significantly improve the survival rate.