治疗溃疡病出血药物的机理是通过减少胃血流量或促进凝血来控制出血。在这方面,已研究了许多药物。1.抗纤维蛋白溶解剂tranexamic acid;已有二篇关于tranexamic acid控制消化性溃疡出血随机性试验的研究报告。在这两项研究中,高危病人均占少数。Barer等的研究表明,尽管tranexamic acid不能明显降低再出血率和外科手术率,却可降低病人的死亡率。第二项研究表明,接受治疗的患者需要进一步输血或急症外科手术的例数均明显减少,而对于降低再出血率却无显著意义.此外,3/69的病人并发血栓性静脉炎。令人费解的是, The mechanism for treating ulcer bleeding is to control bleeding by reducing blood flow or promoting blood clotting. In this regard, many drugs have been studied. 1. Anti-fibrinolytic agent tranexamic acid; There are two studies on tranexamic acid randomized controlled trials of peptic ulcer bleeding. In both studies, high-risk patients accounted for a minority. Barer and other studies have shown that although tranexamic acid can not significantly reduce the rate of rebleeding and surgical rates, but can reduce the patient’s mortality. In the second study, there was a significant reduction in the number of patients who needed further blood transfusion or emergency surgery, but no significant decrease in the rate of rebleeding, and 3/69 patients had thrombophlebitis. Puzzling is that,