In their Letter to the Editor, Wei et al. address on the role of spleen stiffness measurement (SSM) for predicting the late recurrence (＞24 months post-surgery) of hepatocellular carcinoma (HCC) after resection (1). They comment on a recently published manuscript by Marasco and colleagues, who could show that spleen stiffness measured by transient elastography was the only predictor of late HCC recurrence after surgery (2).