溴剂在临床上应用极为普遍,由于长期应用或过量而引起蓄积中毒者时有报导,但在短时间内应用常量而发生过敏反应者则报告较少。我院内科于1962年收治一名心包炎患儿,用溴剂后曾发生典型的增殖性溴疹,即在短时常量治疗时,发生过敏反应。现摘要报告如下,以供参考。患儿于××,男,6个月,山东籍,于1962年1月5日因患支气管肺炎并发心包炎而住院治疗。当时除心、肺等脏器有阳性体征外,全身皮肤正常。病程中(入院后1月)因患儿烦躁不安,而给服三溴片,每日0.3克,历时5日。发现全身有少数散在性粟粒大丘疹样红色皮疹,并于(?)折处有间擦疹,微骚痒。初疑为护理欠妥和链霉素的副作用,乃于用药后第九日停用链霉素,局部塗紫草油,加强护理。约五日后皮疹显著好转(停链霉素第十天),但面部皮疹反加重。故 Bromine is very commonly used clinically, with reports of accumulated poisoning caused by long-term use or overdose, but reports of constant use of allergic reactions in less time are reported less. A hospital in our hospital in 1962 admitted a pericarditis in children, with brominated bromine after a typical case of proliferative bromhidrosis, that is, short-term treatment, the occurrence of allergic reactions. The summary report is as follows for reference. Children in × ×, male, 6 months, Shandong membership, in January 5, 1962 with bronchial pneumonia complicated by pericarditis and hospitalization. At that time in addition to heart, lung and other organs have positive signs, the body skin is normal. Course of disease (January admission) due to irritability in children, and to serving tribromide tablets, 0.3 grams per day, which lasted 5 days. Found that the body has a small number of scattered miliary papules papules like red rash, and (?) At the fold between the rash, micro-itching. Suspected suspicion of nuisance and streptomycin side effects, but discontinued in the ninth day after administration of streptomycin, topical Lithospermum oil, to enhance care. About five days after the rash significant improvement (stop streptomycin tenth day), but the anti-facial rash aggravate. Therefore