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本实验观察医用胶原注射剂注入大鼠皮下后的转归。医用胶原是高度纯化的注射性人胶原，在大鼠皮下可存留１年以上；可诱导大鼠成纤维细胞长入并合成自身胶原，毛细血管长入保障了注射物的血液供应。苦味酸天狼星红－偏振光方法表明，新注射的胶原以纤细的绿色Ⅲ型胶原纤维为主，随着迁入注射物大鼠成纤维细胞合成胶原增加，注射物以粗大的红色Ⅰ型胶原纤维为主，更接近大鼠皮肤正常胶原类型的比例。
The experimental observation of medical collagen injection after subcutaneous injection of rats. Medical collagen is a highly purified injectable human collagen that can survive in the rat subcutaneously for more than one year. It induces fibroblast growth in rats and synthesizes its own collagen. The capillary capillaries ensure the blood supply of the injectables. Picric acid Sirius red - polarized light method shows that the newly injected collagen to slender type III collagen fibers, with the injection of rat fibroblasts into the synthesis of collagen increased, the injection of coarse red type collagen fibers Mainly the proportion of normal collagen type in rat skin.