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编辑同志: 转来杨宝忠、王士富二位医师对《加服小剂量心得安治疗心衰的临床观察》一文所提出的问题己拜读,颇受启发,现就有关问题答复如下: 一、β-受体阻滞剂在心衰中特殊作用的新概念自1975年瑞典学者使用β-受体阻滞剂治疗扩张性心肌病充血性心衰(CHF)取得满意疗效以来,引起国内外临床界的关注,但用于其它心脏病心衰目前尚未得到公认。过去认为,交感神经(SNS)兴奋这一代偿机制在心衰早期占主要地位,而近年来此机制在慢性CHF中则受到重视,业已证明,SNS的慢性激活,给衰竭的心脏提供了应激的变力
Editor’s Comrade: Turn to Yang Baozhong, Wang Shifu Two physicians on the “plus dose of small doses of clinical observation of treatment of heart failure,” a paper presented by the question has been read, very inspired, are the answers to the relevant questions are as follows: New Concept of Body Blocker’s Special Role in Heart Failure Since Swedish scholars used β-blocker to treat dilated cardiomyopathy with congestive heart failure (CHF) in 1975, it has aroused the attention of the clinical community at home and abroad , But the heart failure for other heart disease has not yet been recognized. In the past, the compensatory mechanism of sympathetic nerve (SNS) excitability predominates in the early stages of heart failure, and in recent years this mechanism has gained prominence in chronic CHF, and it has been demonstrated that chronic activation of the SNS provides the failing heart with The power of change