环丙沙星是氟喹诺酮类抗菌药。其作用机制是抑制细菌 DNA 回旋酶,阻断细菌 DNA 正常代谢的信息传递,使细菌的复制能力迅速消失,从而达到杀菌作用。其杀菌力强,抗菌谱广,对革兰阳性、革兰阴性细菌均有较强的杀菌作用。现将我们应用环丙沙星治疗呼吸道感染的治疗效果报道如下。1 病例选择呼吸道感染男18例,女14例,平均年龄36.28岁。其中,上呼吸道感染3例,下呼吸道感染29例(其中局灶性肺炎10例,支气管肺炎8例,慢性支气管炎并感染6例,支气管扩张并感染5例)。32例在治疗前均用过其他的抗菌药,如青霉素、头孢唑啉钠等无效而改用环丙沙星的。所有病例均在治疗前后拍胸部 X 光对照及查血、尿常规。2 治疗方法环丙沙星(广州侨光制药厂,批号96061902)100ml(含0.2g),iv,gtt,bid,疗程为 Ciprofloxacin is a fluoroquinolone antibacterial. Its mechanism of action is inhibition of bacterial DNA gyrase, blocking the normal metabolism of bacterial DNA transmission of information, so that the ability of bacteria to quickly disappear, so as to achieve the bactericidal effect. Its strong bactericidal, broad antibacterial spectrum, Gram-positive, Gram-negative bacteria have a strong bactericidal effect. Now we apply ciprofloxacin treatment of respiratory tract infection reported as follows. A case of respiratory infection in 18 males and 14 females, mean age 36.28 years. Among them, 3 cases of upper respiratory tract infection, 29 cases of lower respiratory tract infection (focal pneumonia in 10 cases, bronchial pneumonia in 8 cases, chronic bronchitis and infection in 6 cases, bronchiectasis and infection in 5 cases). 32 cases were used prior to treatment with other antibacterial drugs, such as penicillin, cefazolin sodium and other invalid use of ciprofloxacin. All cases were taken before and after treatment of chest X-ray control and check blood, urine routine. 2 treatment ciprofloxacin (Guangzhou Qiaopin Pharmaceutical Factory, lot number 96061902) 100ml (containing 0.2g), iv, gtt, bid, treatment was