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抗病毒治疗已被公认为治疗乙型肝炎的重要措施,但抗乙型肝炎病毒(HBV)核苷(酸)类似物在妊娠及哺乳期妇女中应用的安全性尚有许多争议。本文综述了近年来有关核苷(酸)类似物在妊娠及哺乳期妇女中应用的文献,为HBV感染的妊娠及哺乳期妇女的抗病毒治疗和母婴阻断提供更多证据。
Antiviral therapy has been recognized as an important treatment for hepatitis B. However, there is much controversy over the safety of anti-HBV nucleoside analogues in pregnancy and breast-feeding women. This review summarizes the recent literature on the use of nucleoside (acid) analogs in pregnant and lactating women to provide additional evidence for antiviral therapy and maternal-to-infant blockage in pregnant and lactating women with HBV infection.