免疫防御功能的高低是决定机体是否受感染的关键。它包括非特异性和特异性协同发挥抗感染的免疫作用。免疫球蛋白(Ig)是机体特异性免疫系统的重要组成部分,临床上很多小儿感染性疾病与其水平下降或异常有关。早在本世纪初即开始使用Ig进行被动免疫,如用胎盘提取物防治麻疹,继而采用低温乙醇提取法从人血浆中分离Ig,用于治疗麻疹、甲型肝炎、免疫缺陷症和败血症等,从而使Ig的临床应用得到重要进展。 The level of immune defense is the key to determining whether the body is infected. It includes the nonspecific and specific synergistic effects of anti-infective immunity. Immune globulin (Ig) is an important part of the body’s specific immune system, many clinically infectious diseases associated with its level of decline or abnormal. As early as the beginning of this century, Ig was used for passive immunization, such as placental extract to control measles, followed by low temperature ethanol extraction to separate Ig from human plasma for the treatment of measles, hepatitis A, immunodeficiency and sepsis, So that the clinical application of Ig have made important progress.