本文报道一例慢性粒细胞性白血病急性变化,经过化疗以后缓解期长达3年以上,实属罕见,现将病例报道如下: 龚××,女性,25岁,8年前有右眼视力下降,眼底出血,伴有低热,脾肿大达脐下3cm,白细胞高选32,800/μl。骨髓涂片证实为慢性粒细胞性白血病。患者于1978年曾住某医院治疗,先后用用马利兰及6巯嘌呤治疗获完全缓解出院。1986年2月又出现发热,脾肿大肋下3cm,复查骨髓为慢粒急性变,给予静玉红每日口服9粒,6巯嘌呤每天口服100mg,骨髓复查再次缓解。1986年4月患者再度发热,全身关节酸痛,胸骨疼,全身无力,心悸,气急胸闷,骨 This article reports an acute change in chronic myeloid leukemia, after chemotherapy for more than 3 years after the remission, it is rare, the case is now reported as follows: Gong × ×, female, 25 years old, 8 years ago, right eye vision decreased, Fundus hemorrhage, accompanied by fever, splenomegaly up to 3cm below the navel, high white cell selection 32,800 / μl. Bone marrow smears confirmed as chronic myelogenous leukemia. The patient was hospitalized in 1978 and has been treated with either ornithine and 6 mercaptopurine for complete remission. February 1986 and fever, splenomegaly ribs 3cm, check the bone marrow for chronic acute change, give jade jade daily oral administration of 9, 6 mercaptopurine oral 100mg daily, bone marrow re-examination again ease. In April 1986 patients re-fever, body soreness, chest pain, general weakness, palpitations, shortness of breath chest tightness, bone