论文部分内容阅读
本研究旨在探讨局部脑血流（ｒＣＢＦ）断层显像与突发性感音神经性耳聋（简称突聋）的关系和临床价值。方法：对１０例正常志愿者，１９例传导性耳聋及３１例突聋患者在治疗前行ｒＣＢＦ显像并对比分析其显像特点，与同期ＣＴ对照，随访ｒＣＢＦ显像阳性的突聋患者６～１２月并再次行ｒＣＢＦ显像。结果：①突聋组ｒＣＢＦ显像阳性率（８０．６％）明显高于传导性聋组（５．３％）和正常组（０％），其突聋组病灶与正常组织的放射性比值（Ｔ／ＮＴ）（０．５９６８±０．０９８２）明显低于传导性聋（０．９８０９±０．０２９１）和正常组（０．９９０８±０．０３１１）（均Ｐ＜０．０１）；而后两组间ｒＣＢＦ显像阳性率和Ｔ／ＮＴ值无显著性差异（Ｐ＞０．０５）；②ＣＴ对突聋的病灶位于颞横回检出率明显低于ｒＣＢＦ显像（Ｐ＜０．０１）；③突聋患者的Ｔ／ＮＴ值与耳聋的程度有较高的相关性；④ｒＣＢＦ显像呈缺血性改变的突聋患者预后（８１．８２％）优于梗塞性改变者（２１．４３％）（Ｐ＜０．０１）；⑤ｒＣＢＦ断层显像与临床预防观察有较高的一致性（９１．７％）。结论：ｒＣＢＦ断层显像对突聋的病灶检出明显高于ＣＴ，对突聋的诊断和鉴别诊断及预后有重要的临床价值
The purpose of this study was to investigate the relationship and clinical value of regional cerebral blood flow (rCBF) tomographic imaging and sudden sensorineural hearing loss (Sudden deafness). Methods: Ten cases of normal volunteers, 19 cases of conductive deafness and 31 cases of sudden deafness patients before treatment rCBF imaging and comparative analysis of its imaging features, compared with the same period CT control, follow-up rCBF imaging positive deafness patients 6 ~ December and again line rCBF imaging. Results: ① The positive rate of rCBF imaging in sudden deafness group (80.6%) was significantly higher than that in conductive deafness group (5.3%) and normal group (0%), and the radiological ratio T / NT) (0.5968 ± 0.0982) was significantly lower than that of conductive deafness (0.9809 ± 0.0291) and normal group (0.9908 ± 0.0311) (all P <0.01) There was no significant difference between the two groups in the positive rate of rCBF imaging and the value of T / NT (P> 0.05). ② The detection rate of CT in sudden deafness was significantly lower than that in rCBF imaging (P <0.01) ); (3) There was a high correlation between T / NT value and deafness in patients with sudden deafness; (4) The prognosis of patients with sudden deafness with ischemic change of rCBF imaging was superior to those with infarction (81.82%). 43%) (P <0.01). ⑤ The consistency of rCBF imaging and clinical observation was high (91.7%). Conclusion: rCBF tomographic imaging of sudden deaf lesions detected significantly higher than the CT, sudden deafness in the diagnosis and differential diagnosis and prognosis of important clinical value