儿童哮喘为临床常见病和多发病,哮喘病的防治仍然是一个急待解决的问题。糖皮质激素治疗最为有效,特别是吸入激素在许多国家已成为哮喘治疗的一线用药。但其制剂昂贵,吸入技术不易掌握。近年来对氨茶碱治疗哮喘有了新认识,认为其在低血药浓度即具抗炎作用。我们自1996年起开展了长期口服小剂量氨茶碱治疗儿童哮喘,观察结果报告如下。 1 对象与方法 1.1 对象 48例均为天津市儿童医院呼吸科病人,诊断符合1993年全国儿科哮喘协作组所订标准。试验前由主管医师获得患儿父母知情同意。一般情况见表1,3组间具有 Childhood asthma is a common and frequently-occurring disease in clinical practice. The prevention and treatment of asthma is still an urgent problem to be solved. Glucocorticoid treatment is the most effective, and in particular inhaled steroids have become first-line treatments for asthma in many countries. But its preparation is expensive, inhalation technology is not easy to grasp. In recent years, aminophylline treatment of asthma has a new understanding that its low blood concentration that anti-inflammatory effect. We have started a long-term oral low-dose aminophylline treatment of childhood asthma since 1996, the observations are reported below. 1 Subjects and Methods 1.1 Subjects 48 cases of Tianjin Children’s Hospital Respiratory patients diagnosed in line with the 1993 National Pediatric Asthma Collaboration set standards. Prior to the trial, the competent physician obtains the informed consent of the child’s parents. See table 1 and 3 for the general situation