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为了探索口腔粘膜扁平苔藓的病因与治疗方法，本研究应用放射免疫技术及ABC方法对15例与月经周期相关的女性口腔扁平苔藓患者分别检测黄体期血清孕酮的含量及口腔粘膜损害组织中的孕激素受体，并对血清孕酮含量低于正常的女性口腔扁平苔藓患者给予孕酮治疗。结果显示：在15例女性口腔扁平苔藓患者中，孕酮与正常组相比具有高度显著性差异（P＜0．01）；其中孕激素受体阳性为11例；在10例血清孕酮低于正常组且孕激素受体阳性的患者中，对补充孕酮治疗效果均很明显。说明口腔粘膜是孕酮除子宫内膜等靶组织外的又一靶组织，孕酮是通过口腔粘膜中的孕激素受体而发挥其生理作用。
In order to explore the etiology and treatment of oral lichen planus, we used radioimmunoassay and ABC method to detect the contents of serum progesterone in corpus luteum and oral mucosal lesion in 15 cases of oral lichen planus associated with menstrual cycle Progesterone receptor, and progesterone in patients with lower levels of progesterone in the female oral lichen planus. The results showed that among 15 female oral lichen planus patients, progesterone had a highly significant difference compared with the normal group (P <0.01), of which progesterone receptor was positive in 11 cases; in 10 cases, serum progesterone was low In the normal group and progesterone receptor-positive patients, the effect of replacement progesterone treatment are obvious. Oral mucosa is progesterone in addition to the target tissue other than endometrial tissue, another target tissue, progesterone through the oral mucosa progesterone receptor and play its physiological role.