目的观察毫米波辐射后兔眼房水一氧化氮（ＮＯ）及白细胞介素６（ＩＬ６）、白细胞介素８（ＩＬ８）、肿瘤坏死因子（ＴＮＦα）含量的变化，探讨毫米波对眼的损伤机制，为制定毫米波辐射的卫生标准提供实验依据。方法新西兰兔按受辐照后不同取材时间及辐射剂量分组，采用３５ＧＨｚ等幅连续波，辐射兔眼１ｈ，用硝酸酶还原法测定房水ＮＯ，用ＥＬＩＳＡ法测定ＩＬ６、ＩＬ８、ＴＮＦα。结果１０ｍＷ／ｃｍ２毫米波辐射结束后６ｈ，房水ＮＯ含量升高（Ｐ＜０．０１），此效应可持续２４ｈ以上；３５ｍＷ／ｃｍ２及１０ｍＷ／ｃｍ２毫米波辐射结束后２４ｈ内，未发现房水ＩＬ６、ＩＬ８、ＴＮＦα含量的升高。结论低功率３５ＧＨｚ毫米波辐射可引起房水中ＮＯ含量的增高，提示ＮＯ为毫米波致眼损伤的重要因素之一 Objective To observe the changes of the contents of nitric oxide (NO), interleukin 6 (IL6), interleukin 8 (IL8) and tumor necrosis factor α (TNFα) in rabbits aqueous humor after millimeter wave irradiation Millimeter-wave damage to the eye mechanism for the development of health standards millimeter-wave radiation to provide experimental evidence. Methods New Zealand rabbits were irradiated by different time and radiation dose groups, the use of 35GHz amplitude continuous wave irradiation rabbit eyes 1h nitrate reductase determination of nitric oxide aqueous determination of IL 6, IL 8, TNF @. Results After 6 hours of 10 mW / cm2 millimeter wave radiation, the content of NO in aqueous humor increased (P <0.01), and this effect lasted for more than 24 h. Within 35 h and 35 mW / cm2 and 10 mW / cm2, IL 6 water, IL 8, TNF  α content increased. Conclusion Low-power 35GHz millimeter-wave radiation can cause an increase of NO in aqueous humor, suggesting that NO is one of the important factors causing millimeter-wave induced eye damage