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酮症倾向糖尿病（ KPD）是一类以糖尿病酮症酸中毒或自发性酮症起病的糖尿病总称，既包括经典1A型糖尿病、成人隐匿性自身免疫糖尿病、特发性糖尿病，也包括以酮症酸中毒或糖尿病酮症起病的2型糖尿病。多种证据表明 KPD 是一类异质性疾病，KPD 患者在遗传、发病机制、临床表现及β细胞功能储备上均存在差异。 KPD合理分型，对研究其病因、发病机制，及血糖接近正常的缓解期治疗方案具有重要意义。“,”Ketosis-prone diabetes (KPD) is a heterogeneous syndrome characterized by diabetes ketoac-idosis or unprovoked ketosis,which includes classic type 1A diabetes,latent autoimmune diabetes in adults, idiopathic diabetes and type 2 diabetes which with diabetes ketoacidosis or ketosis as onset .There are various of evidences indicating that KPD is a kind of heterogeneous disease,KPD patients have differences in genet-ics,pathogenesis,clinical manifestations,and β-cell function reserves.Reasonable classification of KPD is important to study the etiology,pathogenesis and treatment on near-normoglycemic remission.