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作者在含尘小室中进行动物试验;锰尘浓度为每立方厘米空气含7832粒,其细度、温度几与矿井内相同。动物每日连续暴露6小时,至第七天免去暴露一次。飮食制度如常。暴露时处于安静状态,然后再行活动,动物分组作病理观察如下:(1) 暴露锰尘33—50天的2只豚鼠与2只白鼠肺部全有轻度锰尘沉着病,鼻粘膜有轻度急性卡他性炎症。一只豚鼠有支气管肺炎。(2) 暴露59—77天的3只家兔与1只豚鼠,鼻,喉,气管粘膜有轻度急性卡他性炎症,2只家兔有支气管肺炎,其中一兔的鼻粘膜上复有厚层凝结的渗出物,内有大量白血球,上皮小块坏死。豚鼠则有肺尘沉着病。(3) 暴
The authors conducted animal experiments in dusty chambers; the concentration of manganese dust was 7832 grains per cubic centimeter of air, with the same fineness and temperature as in the mine. Animals were exposed continuously for 6 hours a day, and were not exposed for the seventh day. Eating system as usual. Exposed to a quiet state, and then re-activity, animal grouping for pathological observations are as follows: (1) exposure to manganese dust 33-50 days in two guinea pigs and two white lungs were all mild manganese dust disease, nasal mucosa Mild acute catarrhal inflammation. A guinea pig has bronchial pneumonia. (2) mild acute catarrhal inflammation in 3 rabbits exposed to 59-77 days and 1 guinea pig, nasal, larynx and tracheal mucosa, 2 bronchopneumonia in one rabbit, Thick coagulation exudate, there are a large number of white blood cells, epithelial necrosis. Guinea pigs have pneumoconiosis. (3) violence