论文部分内容阅读
前列腺增生症(BPH)是老年男性常见疾病,治疗BPH的目的是解除增生前列腺组织所致的膀胱颈口梗阻症状及其所诱发的膀胱不稳定性.目前认为BPH导致膀胱颈口梗阻的因素有机械性和动力性两种.虽然外科手术能解除膀胱出口梗阻,但部分病人不适应手术治疗且手术有一定的并发症和死亡率,此外约有20%接受经尿道前列腺切除术治疗的病人,术后症状仍不能得到缓解.因此,BPH的药物治疗受到人们的重视.近年来,通过一系列的实验研究与临床实践,发现a-肾上腺素能受体(简称.a-受体)阻滞剂治疗BPH效果明显.本文拟就此类药物的临床应用作一简要介绍.
Prostate hyperplasia (BPH) is a common disease in elderly men, the purpose of treatment of BPH is to relieve the symptoms of bladder neck obstruction caused by hyperplasia of prostate tissue and the bladder instability induced by it.At present, the factors that cause BPH bladder neck obstruction are Mechanical and dynamic two.Although surgery to relieve bladder outlet obstruction, but some patients do not meet the surgical treatment and surgery have some complications and mortality, in addition to about 20% of patients undergoing transurethral resection of the prostate, Postoperative symptoms can not be alleviated.Therefore, people pay more attention to the treatment of BPH.In recent years, through a series of experimental studies and clinical practice, we found that a-adrenoceptor (referred to as .A-receptor) block Agent treatment of BPH obvious effect.This article intends to make a brief introduction of the clinical application of such drugs.