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目的观察伊托必利联合氟哌噻吨美利曲辛治疗功能性消化不良的疗效。方法符合罗马Ⅲ诊断标准的功能性消化不良患者180例随机分为3组,伊托必利联合氟哌噻吨美利曲辛组(A组)、伊托必利组(B组)和氟哌噻吨美利曲辛组(C组)各60例;伊托必利片50 mg,每日3次,氟哌噻吨美利曲辛2片,每日1次,均口服,疗程均为4 wk。观察3组治疗wk 1、4的疗效并做对比分析。结果治疗1 wk和4 wk后症状改善积分总有效率A组分别为79%和93%,B组为61%和81%,C组为45%和64%。A组均明显高于B、C组,差异有显著意义(P<0.05)。结论伊托必利联合氟哌噻吨美利曲辛治疗功能性消化不良疗效好且起效快。
Objective To observe the curative effect of itopride combined with flupentixol and melitracen on functional dyspepsia. Methods One hundred and eighty patients with functional dyspepsia complying with the diagnostic criteria of Rome Ⅲ were randomly divided into 3 groups: Itopride combined with flupentixol and melitracen (group A), itopride (group B) and fluorine Peritothyme compound melitracen group (C group) 60 cases; itopride tablets 50 mg, 3 times a day, flupentixol MTT twice a day, were orally, were For 4 wk. Observe the curative effect of wk 1,4 in three groups and compare them. Results The total effective rate of symptom improvement after 1 and 4 weeks of treatment was 79% and 93% in group A, 61% and 81% in group B and 45% and 64% in group C, respectively. A group were significantly higher than B, C group, the difference was significant (P <0.05). Conclusion Itopride in combination with flupentixol and melitracen have good curative effect and rapid onset of functional dyspepsia.