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我们测定了43例陈旧性心肌梗塞(OMI)病人和对照组28例的血浆心钠素(ANF)含量变化,分别为32.2.36±46.46 pg/ml、230.26±29.84pg/ml(P>0.05);心功能Ⅲ级者为633.46±163.57pg/ml,较对照组显著升高(P<0.01);左房扩大组和双房扩大组分别为414.49±64.93pg/ml、566.94±262.89pg/ml比心房正常组159.70±15.28pg/ml显著升高(P<0.01);血压升高组比血压正常组明显升高,分别为371.25±73.47 pg/ml、192.75±19.55 pg/ml(P<0.05)。结果表明OMI患者血浆ANF升高,提示该病人可能合并心功能不全,心房扩大或高血压。
We measured changes in plasma ANP levels in 43 patients with obstructive pulmonary infarction (OMI) and controls (32.2.36 ± 46.46 pg / ml, 230.26 ± 29.84 pg / ml, respectively; P> 0.05 ). The level of cardiac function was 633.46 ± 163.57pg / ml, which was significantly higher than that of the control group (P <0.01). The left atrial enlargement group and the double atrial enlargement group were 414.49 ± 64.93pg / ml and 566.94 ± 262.89pg / ml was significantly higher than 159.70 ± 15.28pg / ml in atrial normal group (P <0.01); the blood pressure was significantly higher than that in normal blood group (371.25 ± 73.47 pg / ml, 192.75 ± 19.55 pg / ml, P < 0.05). The results showed that patients with OMI elevated plasma ANF, suggesting that the patient may be associated with cardiac insufficiency, atrial enlargement or hypertension.